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PeproTech重组人BMP-7/OP-1/120-03
PeproTech重组人BMP-7/OP-1/120-03
PeproTech重组人BMP-7/OP-1/120-03

PeproTech重组人BMP-7/OP-1/120-03

 详情说明

PeproTech重组人BMP-7/OP-1/120-03

产地 :美国
品牌: PeproTech
货号: 120-03

规格:2ug/10ug/1mg
保存条件: -20℃
保质期: 1年以上
供应商: 深圳9游总区生物科技有限公司
英文名: Recombinant Human BMP-7/OP-1

Synonyms :

OP-1

Description :

TGF-β family members are key modulators of cell proliferation, differentiation, matrix synthesis, and apoptosis. As implied by their name, BMPs initiate, promote, and regulate the development, growth and remodeling of bone and cartilage. In addition to this role, BMPs are also involved in prenatal development and postnatal growth, remodeling and maintenance of a variety of other tissues and organs. BMP-7, also known as osteogenic protein-1 or OP-1, is a potent bone inducing agent, which in the presence of appropriate osteoconductive carrier (e.g. collagen sponge or synthetic hydroxyapatite) can be used in the treatment of bone defects. A bone-graft substitute, called OP-1TM implant, made of recombinant human BMP-7 associated with bovine bone-derived collagen, has recently been approved by the FDA as a device for treating critical-size bone fractures. The potential use of BMP-7 in dental reconstructive surgeries is currently under investigation. Recombinant human BMP-7 is a 28.8 kDa homodimeric glycoprotein consisting of two 116 amino acid subunits, which correspond to amino acid residues 316 to 431 of the full-length BMP-7 precursor.

Catalog #:

120-03

Source :

CHO cells

Purity :

Greater than 98% by SDS-PAGE gel and HPLC analyses.

Endotoxin Level :

Endotoxin level is less than 0.1 ng per μg (1EU/μg).

Biological Activity :

Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED 50 for this effect is 0.02-0.04 μg/ml.

AA Sequence :

MANVAENSSS DQRQACKKHE LYVSFRDLGW QDWIIAPEGY AAYYCEGECA FPLNSYMNAT NHAIVQTLVH FINPETVPKP CCAPTQLNAI SVLYFDDSSN VILKKYRNMV VRACGCH

PubMed Link :

Country of Origin :

USA

 

 

 

Size A 2µg  
 
Size B 10µg
 
Size C 1mg 00 
 

 


 

Special Sizes: 
Many products can be ordered in custom sizes. Please  to contact with your request.

 

Usage: 
For Research Use Only. Not for use in diagnostic or therapeutic procedures.



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