PeproTech重组小鼠Leptin,货号:450-31
PeproTech重组小鼠Leptin,货号:450-31
PeproTech重组小鼠Leptin,货号:450-31
产地 :美国
品牌 :PeproTech
货号: 450-31
规格:200µg/1000µg/5mg
英文名: Recombinant Murine Leptin
CAS号: 无
供应商: 深圳9游总区生物科技有限公司
保存条件: -20℃
数量: 大量
保质期: 1年以上
Synonyms :
|
Obesity protein (OB)
|
Description :
|
Encoded by the ob (obese) gene, Leptin is an adipose-derived cytokine that suppresses appetite and increases thermogenesis. Leptin exerts its anorectic effect via signaling through a hypothalamic receptor termed OB-R. Leptin has been shown to reduce body weight, food consumption, and plasma glucose levels in various in vivo models. Recombinant murine Leptin is a 16.2 kDa protein containing 147 amino acid residues.
|
Catalog #:
|
450-31
|
Source :
|
E.coli
|
Purity :
|
Greater than 98% by SDS-PAGE gel and HPLC analyses.
|
Endotoxin Level :
|
Endotoxin level is less than 0.1 ng per µg (1EU/µg).
|
Biological Activity :
|
's murine Leptin has been shown to be biologically active in two different mouse obesity models, ob/ob and NZO. Both strains of mice were treated via intraperitoneal injection once daily at a dose of 5 µg Leptin/gm of body weight for 14 days. Significant effects on body weight , food consumption, and plasma glucose levels were observed to saline-treated controls
|
Selected References :
|
|
AA Sequence :
|
MVPIQKVQDD TKTLIKTIVT RINDISHTQS VSAKQRVTGL DFIPGLHPIL SLSKMDQTLA VYQQVLTSLP SQNVLQIAND LENLRDLLHL LAFSKSCSLP QTSGLQKPES LDGVLEASLY STEVVALSRL QGSLQDILQQ LDVSPEC
|
PubMed Link :
|
|
Country of Origin :
|
USA
|
|
|