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PeproTech重组小鼠flt3 Ligand-Long Form,货号:250-31L
PeproTech重组小鼠flt3 Ligand-Long Form,货号:250-31L
PeproTech重组小鼠flt3 Ligand-Long Form,货号:250-31L

PeproTech重组小鼠flt3 Ligand-Long Form,货号:250-31L

 详情说明

PeproTech重组小鼠flt3 Ligand-Long Form,货号:250-31L

产地 :美国
品牌 :PeproTech
货号: 250-31L

规格:2µg/10µg/1mg
数量: 大量
英文名: Recombinant Murine flt3 Ligand-Long Form
保存条件: -20℃
保质期: 1年以上
供应商:深圳9游总区生物科技有限公司

Synonyms :

Fms-related tyrosine kinase 3 ligand

Description :

Flt3-Ligand is a growth factor that regulates proliferation of early hematopoietic cells. Flt3-Ligand binds to cells expressing the tyrosine kinase receptor Flt3. Flt3-Ligand, by itself does not stimulate proliferation of early hematopoietic cells, but synergizes with other CSFs and interleukins to induce growth and differentiation. Unlike SCF, Flt3-Ligand has no activity on mast cells. Multiple isoforms of Flt3-Ligand have been identified. The predominant biologically active form is anchored to the cell surface as the extracellular domain of a transmembrane protein (209 a.a.). The membrane-bound isoform can be proteolytically cleaved to generate a biologically active soluble isoform. Recombinant murine Flt3-Ligand is a soluble 18.6 kDa protein consisting of 163 amino acid residues.

Catalog #:

250-31L

Source :

E.coli

Purity :

Greater than 98% by SDS-PAGE gel and HPLC analyses

Endotoxin Level :

Endotoxin level is less than 0.1 ng per μg (1EU/μg).

Biological Activity :

Determined by the dose-dependent stimulation of the proliferation of human AML5 cells. The expected ED 50 for this effect is 5.0 – 8.0 ng/ml.

Selected References :

AA Sequence :

MTPDCYFSHS PISSNFKVKF RELTDHLLKD YPVTVAVNLQ DEKHCKALWS LFLAQRWIEQ LKTVAGSKMQ TLLEDVNTEI HFVTSCTFQP LPECLRFVQT NISHLLKDTC TQLLALKPCI GKACQNFSRC LEVQCQPDSS TLLPPRSPIA LEATELPEPR PRQ

PubMed Link :

Country of Origin :

USA

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