Synonyms :

Stromal-Cell Derived Factor-1, CXCL12, PBSF

Description :

SDF-1 alpha and beta are stromal derived CXC chemokines, and signal through the CXCR4 receptor. SDF-1alpha and beta chemoattract B and T cells, and have been shown to induce migration of CD34+ stem cells. Additionally, the SDF-1 proteins exert HIV suppressive activity in cells expressing the CXCR4 receptor. Recombinant murine SDF-1alpha is a 7.9 kDa protein containing 68 amino acid residues.

Catalog #:

250-20A

Source :

E.coli

Purity :

Greater than 98% by SDS-PAGE gel and HPLC analyses.

Endotoxin Level :

Endotoxin level is less than 0.1 ng per µg (1EU/µg).

Biological Activity :

Determined by its ability to chemoattract human peripheral blood monocytes using a concentration of 50-100 ng/ml.

Selected References :

AA Sequence :

KPVSLSYRCP CRFFESHIAR ANVKHLKILN TPNCALQIVA RLKNNNRQVC IDPKLKWIQE YLEKALNK

PubMed Link :

Country of Origin :

USA