Peprotech重组大鼠MIP-1alpha (CCL3)/400-15
Peprotech重组大鼠MIP-1alpha (CCL3)/400-15
Peprotech重组大鼠MIP-1alpha (CCL3)/400-15
品牌 ：PEPROTECH
产地 ：美国
货号： 400-15
规格：5µg/20µg/1mg
供应商：深圳9游总区生物科技有限公司
保质期： 1年以上
数量： 大量
英文名： Recombinant Rat MIP-1α (CCL3)
保存条件： -20℃
Recombinant Rat MIP-1α (CCL3)
Catalog Number:
400-15
Synonyms:
Macrophage Inflammatory Protein-1α, CCL3, LD78α
Description:
Both MIP-1α and MIP-1β are structurally and functionally related CC chemokines. They participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells e.g. macrophages, lymphocytes and NK cells. While both MIP-1α and MIP-1β exert similar effects on monocytes their effect on lymphocytes differ; with MIP-1α selectively attracting CD8+ lymphocytes and MIP-1β selectively attracting CD4+ lymphocytes. Additionally, MIP-1α and MIP-1β have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. Both human and murine MIP-1α and MIP-1β are active on human and murine hematopoietic cells. Recombinant rat MIP-1α is a 7.8 kDa protein containing 69 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.
AA Sequence:
APYGADTPTA CCFSYGRQIP RKFIADYFET SSLCSQPGVI FLTKRNRQIC ADPKETWVQE YITELELNA
Source:
E.coli
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Biological Activity:
Determined by its ability to chemoattract rat peritoneal macrophages using a concentration of 50.0-100.0 ng/ml.
Cross Reactivity:
Rat, Human + Rat
Country of Origin:
USA
