PeproTech重组大鼠IL-1alpha/100-01A
PeproTech重组大鼠IL-1alpha/100-01A
PeproTech重组大鼠IL-1alpha/100-01A
品牌 PeproTech
产地 美国
货号: 400-01A
英文名: Recombinant Rat IL-1alpha
规格:2µg/10µg/1mg
数量: 大量
保存条件: -20℃
供应商:深圳9游总区生物科技有限公司
保质期: 1年以上
Synonyms :
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Hematopoietin-1, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), Mononuclear Cell Factor (MCF)
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Description :
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IL-1α is a non-secreted proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1α and IL-1β binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1β is a secreted cytokine, IL-1α is predominantly a cell-associated cytokine. Recombinant rat IL-1α is a 17.7 kDa protein containing 155 amino acid residues.
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Catalog #:
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400-01A
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Source :
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E.coli
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Purity :
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Greater than 98% by SDS-PAGE gel and HPLC analyses.
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Endotoxin Level :
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Endotoxin level is less than 0.1 ng per µg (1EU/µg).
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Biological Activity :
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The ED50 as determined by the dose-dependent proliferation of murine D10S cells is < 0.005 ng/ml, corresponding to a specific activity of > 2 x 108 units/mg.
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Selected References :
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AA Sequence :
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MAPHSFQNNL RYKLIRIVKQ EFIMNDSLNQ NIYVDMDRIH LKAASLNDLQ LEVKFDMYAY SSGGDSKYPV TLKVSNTQLF VSAQGEDKPV LLKEIPETPK LITGSETDLI FFWEKINSKN YFTSAAFPEL LIATKEQSQV HLARGLPSMI DFQIS
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PubMed Link :
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Country of Origin :
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USA
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Size A
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2µg
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Size B
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10µg
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5
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Size C
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1mg
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00
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Special Sizes:
Many products can be ordered in custom sizes. Please to contact with your request.
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Usage:
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
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