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PeproTech重组人Follistatin货号:120-13
PeproTech重组人Follistatin货号:120-13
PeproTech重组人Follistatin货号:120-13

PeproTech重组人Follistatin货号:120-13

 详情说明

PeproTech重组人Follistatin货号:120-13

品牌:PeproTech
产地: 美国
货号: 120-13

规格:5µg/20µg/1mg
保存条件: -20℃
供应商: 深圳9游总区生物科技有限公司
英文名: Recombinant Human Follistatin
保质期: 1年以上

Synonyms :

FS, activins-binding protein

Description :

Follistatin is a secreted protein that binds to ligands of the TGF-β family and regulates their activity by inhibiting their access to signaling receptors. It was originally discovered as activin antagonists whose activity suppresses expression and secretion of the pituitary hormone FSH (follicle stimulating hormone). In addition to being a natural antagonist, follistatin can inhibit the activity of other TGF-β ligands including BMP-2,-4,-6,-7, Myostatin, GDF-11, and TGF-β1. Follistatin is expressed in the pituitary, ovaries, decidual cells of the endometrium, and in some other tissues. Recombinant human Follistatin is a 31.5 kDa protein containing 288 amino acids. Its primary structure contains three cysteine-rich domains (called FS domains), each followed by a protease-inhibitory kazal domain.

Catalog #:

120-13

Source :

E.coli

Purity :

Greater than 95% by SDS-PAGE gel and HPLC analyses.

Endotoxin Level :

Endotoxin level is less than 0.1 ng per µg (1EU/µg).

Biological Activity :

Determined by its ability to neutralize Activin A inhibitory effect of murine MPC-11 cells. The expected ED 50 is 0.1-0.4 µg/ml in the presence of 7.5 ng/ml Activin A.

Selected References :

AA Sequence :

GNCWLRQAKN GRCQVLYKTE LSKEECCSTG RLSTSWTEED VNDNTLFKWM IFNGGAPNCI PCKETCENVD CGPGKKCRMN KKNKPRCVCA PDCSNITWKG PVCGLDGKTY RNECALLKAR CKEQPELEVQ YQGRCKKTCR DVFCPGSSTC VVDQTNNAYC VTCNRICPEP ASSEQYLCGN DGVTYSSACH LRKATCLLGR SIGLAYEGKC IKAKSCEDIQ CTGGKKCLWD FKVGRGRCSL CDELCPDSKS DEPVCASDNA TYASECAMKE AACSSGVLLE VKHSGSCN

PubMed Link :

Country of Origin :

USA

   

 

 

Size A 5µg    
 
Size B 20µg  
 
Size C 1mg 00   
 

 

 

 

Special Sizes: 
Many products can be ordered in custom sizes. Please  to contact with your request.

 

Usage:
For Research Use Only. Not for use in diagnostic or therapeutic procedures.



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