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PeproTech重组人sCD14/110-01
PeproTech重组人sCD14/110-01
PeproTech重组人sCD14/110-01

PeproTech重组人sCD14/110-01

 详情说明

PeproTech重组人sCD14/110-01

品牌 :PeproTech
产地 :美国

货号: 110-01

规格:5ug/25ug/1mg
保质期: 1年以上
供应商:深圳9游总区生物科技有限公司
保存条件: -20℃
英文名: Recombinant Human sCD14

Synonyms :

soluble CD14

Description :

CD14 is a cell surface anchored glycoprotein that is expressed predominantly by monocytes and tissue macrophages. CD14 associates with MD-2 (LY-96) and TLR4 to form a receptor complex, which signals specifically in response to bacterial lipopolysaccharide (LPS) binding. The CD14/MD-2/TLR4 receptor complex signals via MyD88, TIRAP, and TRAF6, and ultimately activates NF-kappa-β. CD14 also exists in a soluble form, designated as sCD14, which is capable of specifically binding LPS in the extracellular space. Recombinant sCD14 is a 331 amino acid glycoprotein comprising the extracellular portion of the CD14 receptor.

Catalog #:

110-01

Source :

293 cells

Purity :

Greater than 95% by SDS-PAGE gel and HPLC analyses.

Endotoxin Level :

Endotoxin level is less than 0.1 ng per μg (1EU/μg).

Biological Activity :

Determined by the dose dependent activation of NF-kappaB in a RAW264 cell line based reporter system, using a sCD14 concentration range of 20 ng/μl to 200 ng/μl. The NF-kappaB activation is enhanced when the assay is done in the presence of 0.25 ng/μl to 1.0 ng/μl bacterial LPS.

AA Sequence :

TTPEPCELDD EDFRCVCNFS EPQPDWSEAF QCVSAVEVEI HAGGLNLEPF LKRVDADADP RQYADTVKAL RVRRLTVGAA QVPAQLLVGA LRVLAYSRLK ELTLEDLKIT GTMPPLPLEA TGLALSSLRL RNVSWATGRS WLAELQQWLK PGLKVLSIAQ AHSPAFSCEQ VRAFPALTSL DLSDNPGLGE RGLMAALCPH KFPAIQNLAL RNTGMETPTG VCAALAAAGV QPHSLDLSHN SLRATVNPSA PRCMWSSALN SLNLSFAGLE QVPKGLPAKL RVLDLSCNRL NRAPQPDELP EVDNLTLDGN PFLVPGTALP HEGSMNSGVV P

PubMed Link :

Country of Origin :

USA

 

 

 

Size A 10µg  
 
Size B 50µg
 
Size C 1mg 00 
 

 


 

Special Sizes: 
Many products can be ordered in custom sizes. Please  to contact with your request.

 

Usage: 
For Research Use Only. Not for use in diagnostic or therapeutic procedures.




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