PeproTech重组人VEGF-D/100-20D
PeproTech重组人VEGF-D/100-20D
PeproTech重组人VEGF-D/100-20D
品牌 :PeproTech
产地: 美国
货号: 100-20D
规格:2ug/10ug/1mg
英文名: Recombinant Human VEGF-D
供应商: 深圳9游总区生物科技有限公司
保存条件: -20℃
保质期: 1年以上
Synonyms :
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Vascular Endothelial Growth Factor-D, FIGF
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Description :
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VEGF-D, a member of the VEGF/PDGF family of structurally related proteins, is a potent angiogenic cytokine. It promotes endothelial cell growth, promotes lymphangiogesis, and can also affect vascular permeability. VEGF-D is highly expressed in the lung, heart, small intestine and fetal lung, and at lower levels in the skeletal muscle, colon, and pancreas. It forms cell surfaced-associated non-covalent disulfide linked homodimers, and can bind and activate both VEGFR-2 (flk1) and VEGFR-3 (flt4) receptors. During embryogenesis, VEGF-D may play a role in the formation of the venous and lymphatic vascular systems. It also participates in the growth and maintenance of differentiated lymphatic endothelium in adults. Both VEGF-C and VEGF-D are over-expressed in certain cancers, and the resulting elevated levels of VEGF-C or VEGF-D tend to correlate with increased lymphatic metastasis. Recombinant human VEGF-D is a 13.1 kDa non-disulfide linked homodimeric protein consisting of two 117 amino acid polypeptide chains. Due to glycosylation the protein migrates as a 20.0-22.0 kDa band under non-reducing condition.
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Catalog #:
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100-20D
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Source :
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293 cells
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Purity :
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Greater than 95% by SDS-PAGE gel and HPLC analyses.
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Endotoxin Level :
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Endotoxin level is less than 0.1 ng per μg (1EU/μg).
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Biological Activity :
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Testing in progress.
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AA Sequence :
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FAATFYDIET LKVIDEEWQR TQCSPRETCV EVASELGKST NTFFKPPCVN VFRCGGCCNE ESLICMNTST SYISKQLFEI SVPLTSVPEL VPVKVANHTG CKCLPTAPRH PYSIIRR
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PubMed Link :
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Country of Origin :
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USA
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Size A
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2µg
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Size B
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10µg
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5
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Size C
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1mg
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00
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Special Sizes:
Many products can be ordered in custom sizes. Please to contact with your request.
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Usage:
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
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