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PeproTech重组人PDGF-BB(无动物成分)/AF-100-14B
PeproTech重组人PDGF-BB(无动物成分)/AF-100-14B
PeproTech重组人PDGF-BB(无动物成分)/AF-100-14B

PeproTech重组人PDGF-BB(无动物成分)/AF-100-14B

 详情说明

PeproTech重组人PDGF-BB(无动物成分)/AF-100-14B

品牌 :PeproTech
产地 :美国

货号:AF-100-14B-100

规格:10µg/1mg
供应商:深圳9游总区生物科技有限公司
保质期: 1年以上
英文名: Recombinant Human PDGF-BB
CAS号:
保存条件: -20℃

Synonyms :

Platelet-Derived Growth Factor-BB, Glioma-derived growth factor (GDGF), Osteosarcoma-derived Growth Factor (ODGF)

Description :

PDGFs are disulfide-linked dimers consisting of two 12.0-13.5 kDa polypeptide chains, designated PDGF-A and PDGF-B chains. The three naturally occurring PDGFs; PDGF-AA, PDGF-BB and PDGF-AB, are potent mitogens for a variety of cell types including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. The PDGFs are stored in platelet α-granules and are released upon platelet activation. The PDGFs are involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development. Two distinct signaling receptors used by PDGFs have been identified and named PDGFR-α and PDGFR-β. PDGFR-α is high-affinity receptor for each of the three PDGF forms. On the other hand, PDGFR-β interacts with only PDGF-BB and PDGF-AB. Recombinant human PDGF-BB is a 24.3 kDa disulfide-linked homodimer of two B chains (218 total amino acids). Manufactured using all non-animal reagents .

Catalog #:

AF-100-14B

Source :

E.coli

Purity :

Greater than 98% by SDS-PAGE gel and HPLC analyses.

Endotoxin Level :

Endotoxin level is less than 0.1 ng per μg (1EU/μg).

Biological Activity :

Determined by the dose-dependent stimulation of the proliferation of Balb/c 3T3 cells. The expected ED 50 for this effect is 1.0-3.0 ng/ml.

AA Sequence :

SLGSLTIAEP AMIAECKTRT EVFEISRRLI DRTNANFLVW PPCVEVQRCS GCCNNRNVQC RPTQVQLRPV QVRKIEIVRK KPIFKKATVT LEDHLACKCE TVAAARPVT

PubMed Link :

Country of Origin :

USA

 

 

 

Size B 10µg  
 
Size C 1mg 00   
 

 


 

Special Sizes: 
Many products can be ordered in custom sizes. Please  to contact with your request.

 

Usage: 
For Research Use Only. Not for use in diagnostic or therapeutic procedures.



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