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PeproTech重组人IGF-I (Animal Free) /AF-100-11
PeproTech重组人IGF-I (Animal Free) /AF-100-11
PeproTech重组人IGF-I (Animal Free) /AF-100-11

PeproTech重组人IGF-I (Animal Free) /AF-100-11

 详情说明

PeproTech重组人IGF-I (Animal Free) /AF-100-11

产地: 美国
品牌 :PeproTech
货号: AF-100-11
保质期: 1年以上

规格:100µg/1mg
保存条件: -20℃
数量: 大量
供应商: PeproTech(派普泰克)
英文名: Recombinant Human IGF-I

Synonyms :

Insulin-like Growth Factor-I, Somatamedin C, IGF-IA

Description :

The IGFs are mitogenic polypeptide growth factors that stimulate the proliferation and survival of various cell types including muscle, bone, and cartilage tissue in vitro. IGFs are predominantly produced by the liver, although a variety of tissues produce the IGFs at distinctive times. The IGFs belong to the Insulin gene family, which also contains insulin and relaxin. The IGFs are similar by structure and function to insulin, but have a much higher growth-promoting activity than insulin. IGF-II expression is influenced by placenta lactogen, while IGF-I expression is regulated by growth hormone. Both IGF-I and IGF-II signal through the tyrosine kinase type I receptor (IGF-IR), but, IGF-II can also signal through the IGF-II/Mannose-6-phosphate receptor. Mature IGFs are generated by proteolytic processing of inactive precursor proteins, which contain N-terminal and C-terminal propeptide regions. Recombinant human IGF-I and IGF-II are globular proteins containing 70 and 67 amino acids, respectively, and 3 intra-molecular disulfide bonds. Manufactured using all non-animal reagents.

Catalog #:

AF-100-11

Source :

E.coli

Purity :

Greater than 98% by SDS-PAGE gel and HPLC analyses.

Endotoxin Level :

Endotoxin level is less than 0.1 ng per μg (1EU/μg).

Biological Activity :

The ED 50 was determined by a cell proliferation assay using FDC-P1 cells is ≤ 2.0 ng/ml, corresponding to a specific activity of ≥ 5 x 105 units/mg.

AA Sequence :

GPETLCGAEL VDALQFVCGD RGFYFNKPTG YGSSSRRAPQ TGIVDECCFR SCDLRRLEMY CAPLKPAKSA

PubMed Link :

Country of Origin :

USA

 

 

 

Size B 100µg
 
Size C 1mg
 

 


 

Special Sizes: 
Many products can be ordered in custom sizes. Please  to contact with your request.

 

Usage: 
For Research Use Only. Not for use in diagnostic or therapeutic procedures.


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