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PeproTech重组人IGF Binding Protein-3/100-08
PeproTech重组人IGF Binding Protein-3/100-08
PeproTech重组人IGF Binding Protein-3/100-08

PeproTech重组人IGF Binding Protein-3/100-08

 详情说明

PeproTech重组人IGF Binding Protein-3/100-08

产地 :美国
品牌: PeproTech
货号: 100-08
英文名: Recombinant Human IGF Binding Protein-3

中文:重组人胰岛素样生长因子结合蛋白-3

规格:5µg/25µg/1mg
CAS号:
供应商:深圳9游总区生物科技有限公司
保质期: 1年以上
保存条件: -20℃

Synonyms :

Insulin-like Growth Factor-Binding Protein 3, Growth-hormone-dependant binding protein

Description :

IGF-BP3 is a 30 kDa cysteine-rich secreted protein. It is the major IGF binding protein present in the plasma of human and animals and it is also found in α-granules of platelets. In addition to its ability to modulate the activity of IGF-I and IGF-II, IGF-BP3 exerts inhibitory effects on follicle stimulating hormone (FSH) activity. Decreased plasma levels of IGF-BP3 often results in dwarfism, whereas elevated levels of IGF-BP3 may lead to acromegaly. The expression of IGF-BP3 in fibroblasts is stimulated by mitogenic growth factors such as Bombesin, Vasopressin, PDGF, and EGF. Recombinant human IGF-BP3 is a 28.8 kDa protein consisting of 264 amino acid residues.

Catalog #:

100-08

Source :

E.coli

Purity :

Greater than 98% by SDS-PAGE gel and HPLC analyses.

Endotoxin Level :

Endotoxin level is less than 0.1 ng per µg (1EU/µg).

Biological Activity :

The ED 50 was determined by its ability to inhibit IGF-II induced proliferation of MCF-7. The expected ED 50 for this effect is ≤ 0.2 µg/ml in presence of 15 ng/ml of human IGF-II.

AA Sequence :

GASSGGLGPV VRCEPCDARA LAQCAPPPAV CAELVREPGC GCCLTCALSE GQPCGIYTER CGSGLRCQPS PDEARPLQAL LDGRGLCVNA SAVSRLRAYL LPAPPAPGNA SESEEDRSAG EVESPSVSST HRVSDPKFHP LHSKIIIIKK GHAKDSQRYK VDYESQSTDT QNFSSESKRE TEYGPCRREM EDTLNHLKFL NVLSPRGVHI PNCDKKGFYK KKQCRPSKGR KRGFCWCVDK YGQPLPGYTT KGKEDVHCYS MQSK

PubMed Link :

Country of Origin :

USA

 

 

 

Size A 5µg -- 
 
Size B 25µg --
 
Size C 1mg -- 
 

 


 

Special Sizes: 
Many products can be ordered in custom sizes. Please  to contact with your request.

 

Usage: 
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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