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PeproTech重组人Epiregulin/100-04
PeproTech重组人Epiregulin/100-04
PeproTech重组人Epiregulin/100-04

PeproTech重组人Epiregulin/100-04

 详情说明

PeproTech重组人Epiregulin/100-04

产地: 美国
品牌: PeproTech
货号: 100-04

规格:5ug/25ug/1mg
英文名: Recombinant Human Epiregulin
保存条件: -20℃
供应商:深圳9游总区生物科技有限公司
保质期: 1年以上

Synonyms :

EREG

Description :

Epiregulin is an EGF related growth factor that binds specifically to EGFR (ErbB1) and ErbB4, but not ErbB2 or ErbB3. It is expressed mainly in the placenta and peripheral blood leukocytes and in certain carcinomas of the bladder, lung, kidney and colon. Epiregulin stimulates the proliferation of keratinocytes, hepatocytes, fibroblasts and vascular smooth muscle cells. It also inhibits the growth of several tumor-derived epithelial cell lines. Human Epiregulin is initially synthesized as a glycosylated 19.0 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce a 6.0 kDa mature secreted sequence. Recombinant human Epiregulin is a 5.6 kDa monomeric protein, containing 50 amino residues, which corresponds to the mature secreted Epiregulin sequence.

Catalog #:

100-04

Source :

E.coli

Purity :

Greater than 98% by SDS-PAGE gel and HPLC analyses.

Endotoxin Level :

Endotoxin level is less than 0.1 ng per μg (1EU/μg).

Biological Activity :

The ED 50 was determined by the dose-dependent stimulation of the proliferation of murine Balb/3T3 cells is ≤ 2.0 ng/ml, corresponding to a specific activity of ≥ 5 x 105 units/mg.

AA Sequence :

MVAQVSITKC SSDMNGYCLH GQCIYLVDMS QNYCRCEVGY TGVRCEHFFL

PubMed Link :

Country of Origin :

USA

 

 

 

Size A 5µg  
 
Size B 25µg
 
Size C 1mg 00 
 

 


 

Special Sizes: 
Many products can be ordered in custom sizes. Please  to contact with your request.

 

Usage: 
For Research Use Only. Not for use in diagnostic or therapeutic procedures.



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