兔抗鸡IgY抗体

产品货号ZK-0432R
英文名称Rabbit Anti-Chicken IgY
中文名称兔抗鸡IgY抗体
别    名Egg yolk immunoglobulin; IgY.  
规格    1mg  10mg
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Chicken, 
产品应用WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量180kDa
性    状Lyophilized or Liquid
浓    度1mg/ml
免 疫 原Chicken IgY: 
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M PBS(pH7.4)
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍background:
In chickens, immunoglobulin Y is the functional equivalent to Immunoglobulin G (IgG). Like IgG, it is composed of two light and two heavy chains. Structurally, these two types of immunoglobulin differ primarily in the heavy chains, which in IgY have a molecular mass of about 65,100 atomic mass units (amu), and are thus larger than in IgG. The light chains in IgY, with a molar mass of about 18,700 amu, are somewhat smaller than the light chains in IgG. The molar mass of IgY thus amounts to about 167,000 amu. The steric flexibility of the IgY molecule is less than that of IgG.Functionally, IgY is partially comparable to Immunoglobulin E (IgE), as well as to IgG. However, in contrast to IgG, IgY does not bind to Protein A, to Protein G, or to cellular Fc receptors. Furthermore, IgY does not activate the complement system. The name Immunoglobulin Y was suggested in 1969 by G.A. Leslie and L.W. Clem, after they were able to show differences between the immunoglobulins found in chicken eggs, and immunoglobulin G. Other synonymous names are Chicken IgG, Egg Yolk IgG, and 7S-IgG.

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

鸡卵黄免疫球蛋白G抗体是一种7S免疫球蛋白，与哺乳动物IgG略有不同。该蛋白质分子量约为180kDa，含两个亚单位，即67～70kDa的重链和22～30kDa的轻链，又称IgY（Yolk immunoglobulin），存在于免疫后母鸡的卵黄中。