兔抗小鼠k-链抗血清

产品货号：ZK-0330Rs
英文名称：Rabbit anti-mouse Kappa Chain whole serum
中文名称：兔抗小鼠k-链抗血清
规格      :1ml  
抗体来源：Rabbit
克隆类型：Polyclonal
交叉反应： Mouse, 
产品应用：WB=1:10000-50000 ELISA=1:10000-100000 IHC-P=1:10000-50000 IHC-F=1:10000-50000  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
性    状：lyophilized powder
免 疫 原：mouse kappa chain protein purified from serum: 
亚    型：whole antiserum
纯化方法：Unpurified
储 存 液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
产品介绍background:
Immunoglobulins belong to a group of related glyco proteins which make up 20% of serum proteins. Antigens and immunoglobulins react to confer immunity to individuals. Immunoglobulins have similar structures of two identical heavy chains and two identical light chains. Both the heavy chains and the light chains are divided into constant and variable regions. The constant regions have the same amino acid sequences between all the immunoglobulin classes. The variable regions have approximately 110 amino acids with high sequence variability. The amino acid sequence of the heavy chain determines the class of an immunoglobulin. The five types of immunoglobulin heavy chains are known as: IgG, IgA, IgM, IgD, and IgE. IgG is divided into four subclasses, and IgA is divided into two subclasses. In serum IgA and IgG are monomers with a single 4 polypeptide unit; while, IgM is a pen tamer. IgA may also form polymers. Kappa light chain antibody can be used for the identification of leukemias, plasmacytomas and certain non Hodgkin's lymphomas. Kappa light chain contains one immunoglobulin like domain. The EU sequence has the INV allotypic marker, Ala 45 and Val 83. The ROY sequence has the INV allotypic marker, Ala 45 and Leu 83.