兔抗小鼠IgM抗血清

产品货号：ZK-0368Rs
英文名称：Rabbit anti-mouse IgM whole serum
中文名称：兔抗小鼠IgM抗血清
规格    ：1ml  10ml  
克隆类型：Polyclonal
交叉反应： mo
产品应用：WB=1:10000-50000 ELISA=1:10000-100000 IHC-P=1:10000-50000 IHC-F=1:10000-50000  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
储 存 液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
产品介绍background:
IgM normally constitutes about 10% of serum immunoglobulins. IgM antibody is prominent in early immune responses to most antigens and is largely confined to plasma due to it's large size. Monomeric IgM is expressed as a membrane bound antibody on the surface of B cells and as a pentamer when secreted by plasma cells. Due to it's high valency IgM is more efficient than other isotypes is binding antigens with repeating epitopes (virus particles and red blood cells) and is more efficient than IgG in activiating the complement pathway. The gene for the mu constant region contains four domains separated by short intervening sequences.